Summary of Research Publications / Reviews/ Abstracts / Patents:

1. Inventors: Ramapati Tripathi, Vinod Kumar Tiwari, Arvind Kumar Srivastava, Kavita Arora, Sapana Gupta, K P Murthy, R D Walter: A process for the preparation of novel N¹, Nⁿ-diglycosylated diamino alkanes useful in chemotherapy of filarial infections. (INF/PAT/05/2001)

2. Inventors: Ramapati Tripathi, Vinod Kumar Tiwari, Arvind Kumar Srivastava, Kavita Arora, Sapana Gupta, KP Murthy, R D Walter: N¹, Nⁿ-diglycosylated diamino alkanes useful in chemotherapy of filarial infectious, (INF/PAT/06/2001)

3. Inventors: Ramapati Tripathi, Vinod Kumar Tiwari, Ramchandra Mishra, Ranjana Srivastava, Sudhir Sriwastava, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava: A process for the preparation of novel combinatorial library of N¹ - glycosylated and N³ - substituted ureas and thioureas useful as antitubercular agents, (NF / 476 / 01).

4. Inventors: Ramapati Tripathi, Vinod Kumar Tiwari, Ram chandra Mishra, Ranjana Srivastava, Sudhir Sriwastava, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava: Novel combinatorial library of N¹ – glycosylated and N³ –substituted ureas and thioureas useful as antitubercular agents, (NF / 474 / 01).

 5. Inventors: Ramapati Tripathi, Vinod Kumar Tiwari, Neetu Tewari, Ranjana Srivastava, Sudhir Srivastava, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava: Diglycosylated diaminoalcohol as novel antitubercular agents. (NF/348/02);

6. Inventors: Ramapati Tripathi, Vinod Kumar Tiwari, Neetu Tewari, Ranjana Srivastava, Sudhir Sinha, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava:  A process for the preparation of diglycosylated diaminoalcohol as antitubercular agents.  (NF/349/02).

7. Inventors: Ramapati Tripathi, Vinod Kumar Tiwari, Diksha Katiyar, Neetu Tewari, Anil Gaikwad, Sudhir Sinha, Vinita Chaturvedi, Anil Srivastava, Ranjana Srivastava, Brahm Shankar Srivastava: A process for the synthesis of novel glycosylated aminoalcohol as antitubercular agents.  (NF/08/03).

8. Inventors: Ramapati Tripathi, Vinod Kumar Tiwari, Diksha Katiyar, Neetu Tewari, Anil Gaikwad, Sudhir Sinha, Vinita Chaturvedi, Anil Srivastava, Ranjana Srivastava, Brahm Shankar Srivastava: Novel glycosylated aminoalcohol useful in the chemotherapy of tubercuosis, (NF/09/03).

(B) List of Publications:

9. Unexpected Isomerisation of Double bond with DBU: A Convenient Synthesis of     Tetrasubstituted a-alkylidene tetrahydrofuranoses V K Tiwari and R P Tripathi, Indian J. Chem, 41 B, 2002, 1681-1685.

10. Conjugate addition of amines to sugar derived olefinic ester: synthesis of glycosylated amino esters as DNA Topoisomerase–II Inhibitors, A R Khan, R P Tripathi, V K Tiwari, R C Mishra, V J M Reddy and J K Saxena, J. Carbohydrate Chemistry, 2002, 21(6), 587-600.

11. Synthesis of Glycosylated b-amino acids as new class of antitubercular agents, R P Tripathi, R Tripathi, V K Tiwari, L Bala, S Sinha, A Srivastava, R Srivastava, B S Srivastava, Eur. J. Medicinal Chemistry, 37, 9, (2002), 773-781.

12. DBU/ TBAB/4A⁰ Catalysed cyclatic amidation reactions: A highly efficient & convenient synthesis of C-Nucleosides. N Tewari, R C Mishra, V K Tiwari, R P Tripathi, Synlett, 2002,11, 1779-1782.

13.Unexpected Isomerisation reaction with DBU: An easy access to a-alkylidene tetrahydrofuranose V K Tiwari and R P Tripathi, Medicinal Chemistry Research, 2001, 10, 548

14. DBU Assisted Cyclorelease Elimination: Combinatorial Synthesis and g-glutamyl cystein synthetase  & glutathione-S- transeferase Modulatory Activity of C- nucleoside analogs R C Mishra, N Tewari, K Arora, R Ahmad, R P Tripathi, V K Tiwari, R D Walter and A K Srivatava, Combi Chem & Highthroughtput Screening, 2003, 6, 36-51.

15. 7-O- (4-methyl piperazin-acetyl)-4-methyl-2H-1-benzopyran-2-ones: A novel lead compound for antifilarial activity, R P Tripathi, V K Tiwari, S Bhattacharya, K Srivastava, V M L Srivastava and K Murty, Acta Tropica, 2003, 87, 215-224.

16. Synthesis and antifilarial evaluation of 7-O- acetamidyl-4-alkyl-2H-1-benzopyran-2-ones: D Katiyar, V K Tiwari, R P Tripathi, V J M Reddy, S Bhattacharya, J K Saxena, Drug Research, 2003, 53, 12, 857-863.

17. Synthesis and Antifilarial Evaluation of N¹, Nⁿ- Diglycosylated Diaminoalkanes, V K Tiwari, N   Tewari, R P Tripathi, K Arora, S Gupta, A K Srivastava, A Khan and P K  Murthy, R D Walter Bio. Med. Chem., 2003, 11, 1789.

18. Synthesis and bioevaluation of glycosyl ureas as a-glucosidase inhibitors and their effect on Mycobacterium, N Tewari, V K Tiwari, R C Mishra, R P Tripathi, A K Srivastava, R Ahmad, R Srivastava and B S Srivastava, Bio. Med. Chem., 2003, 11, 2911-2922.

19. Synthesis and Antimycobacterial Activity of 3,5-Disubstituted Thiadiazine thiones, D Katiyar, V K Tiwari, R. P. Tripathi, A K Srivastava, V Chaturvedi, R Srivastava and B S Srivastava, Bio. Med. Chem., 2003, 11, 4369-4375.

20. Amberlite IR -120 Catalysed Efficient Synthesis of Glycosyl Enaminones and their Application, N Tewari, D Katiyar, V K Tiwari and R P Tripathi, Tetrahedron Lett., 2003, 44, 6639-6642.

21. An efficient syntheses of a-mannosylated phenolics as a-glycosidase inhibitors, A R Khan, V K Tiwari, A K Srivastava, R Ahmad, R P Tripathi, J. Enzyme Inhibition and Medicinal Chemistry, 2004, 19, 107-112.

22. Synthesis of Galactopyranosyl Amino Alcohols as a new class of Antitubercular and      antifungal agents, N Tewari, V K Tiwari, R P Tripathi, A. Gaikwad, S Sinha, A K Chaturvedi, P K Shukla, R. Srivastava and B S Srivastava, Bio. Med. Chem. Lett, 2003, 14, 329-332.

 23.Combinatorial and conventional synthesis of glycohybrid molecules as new class of anti tubercular agents. V K Tiwari, R P Tripathi, V Chaturvedi, A Srivastava, S Sinha, R. Srivastava, B S Srivastava, Medicinal Chemistry Research, 2003, 12, 394.

24. Inhibitors of filarial g-glutamyl cycle enzymes as possible macrofilaricidal agents, S Gupta, K Arora, V K Tiwari, R P Tripathi, A K Srivastava, R D Walter, Medicinal Chemistry Research, 2003, 12, 363.

25. Combinatorial synthesis of glycohybrid molecules as potential chemotheraupetic agents, R C Mishra, V K Tiwari, R P Tripathi, Medicinal Chemistry Research, 2003, 12, 336.

26. Inhibitors of filarial g-glutamyl cycle enzymes as possible macrofilaricidal agents, S Gupta, K Arora, V K Tiwari, D Katiyar, R P Tripathi, A K Srivastava, Rolf D Walter, communicated to Medicinal Chemistry Research, 2004, 13 (8/9), 707-723.

27. One pot amberlite IR-120 catalysed synthesis of glycosyl pyridinone, N Tewari, V K Tiwari and R. P. Tripathi, Tetrahedron Lett., (2006, Communicated).

 28. Synthesis and antimycobacterial activity of glycosylated b-amino alcohols and amines, D Katiyar, V K Tiwari, N Tiwari, S S Verma, S Sinha, A Giakwad, A Srivastava, V Chaturvedi, R Srivastava, B S Srivastava, R P Tripathi, Eu. J.  Med Chem. 2005, 40, 351-360.

29. Synthesis and antitubercular activities of bis-glycosylated diamino alcohols, R P Tripathi, V K Tiwari, N Tewari, D Katiyar, N Saxena, S Sinha, A Gaikwad, A Srivastava, V Chaturvedi, Y K Manju, R Srivastava, R Srivastava, B S Srivastava, Bio-Org. Med. Chem., 2005, 13, 5668-5679.

30. Solid phase synthesis and antitubercular activity of glycosyl carboxamides, R P Tripathi, V K Tiwari, B S Srivastava, Bio Org.  Med. Chem. (2006, for CDRI communication)

31.An efficient synthesis of aryloxyphenyl cyclopropyl methanones: A new class of anti-mycobacterial agents.Tewari N; Dwivedi, Tiwari, V. K.; Chaturvedi, V; Manju, Y. K.; Srivastava, A.; Giakwad, A.; Sinha, S.; Tripathi, R. P. (2005): Bio-Organic & Medicinal Chemistry Letters, 15 (20), 4526-4530.

32. Search of new drugs for tuberculosis: Glycosylated b-amino acids as new class of antitubercular agents, V K Tiwari, R P Tripathi, R Tripathi, L Bala, S Sinha, A Srivastava, R Srivastava, B S Srivastava, Trends Carbohyd.  Chem. 8, 67-76, 2002.

33. Synthesis and Antitubercular Activities of S-Glycosyl Mercaptans, V K Tiwari, B. K. Singh, V. Chaturvedi, Y.K. Manju, A.K. Srivatava, S.S. Sinha, A. Gaikwad  & R P Tripathi, Med. Chem.: An Ind J. (2007, in press)

34. Fighting Tuberculosis:  An old disease with new challenges, R P Tripathi, N. Tewari, N.  Dwivedi, V K Tiwari  (2005, Medicinal Research Review, 2005, 25, 1, 93-131.

35. Synthesis and antitubercular activity of substituted phenylmethyl- and pyridylmethyl amines: R. P. Tripathi, Nisha Saxena, V. K. Tiwari, S. S. Verma, Vinita Chaturvedi, Y. K. Manju, A. K. Srivastva, A. Gaikwad and S. Sinha, Bio Org Med Chem., 2006, 14,
8186–8196.

36. Recent application of thioamides in Hetercyclisation, V K Tiwari, A Singh (2007, Tetrahedron, under preparation)

37. Solvent Free Organic Synthesis: A Stereocontrolled Approach, V K Tiwari (2007, Current Organic Chemistry, under preparation)

38.  Study of pollution related problems in river Ganga: water treatment action plan and waste management at Kanpur, Desh D Singh,¹ A lamba,² S Mishra,³ V K Tiwari ^4* (2007, Earth)

39. Antituberculosis agents emerging from Natural Products, V K Tiwari, D D Singh, B B Mishra, V J Tripathi (2007, Current Medicinal Chemistry, under preparation)

40. Synthesis and antifungal activity of 2- (1’, 4’)-Phenylene-bis-5-Substituted Aryl Amino-[1,2,4] Thiadiazol-3-One. Tiwari V. K.; Singh D. D.; Mishra B. (2007):, Ind. J. Chem. (Ready for submission).

41. A convenient one pot benzotriazole mediated synthesis of Quinazolinones, Vinod K Tiwari, ^* H A Hussain, B B Mishra, D D Singh, V J Tripathi (2007, Letter in  Org. Chem. manuscript under preparation).

42. Benzotriazole mediated one pot convenient synthesis of dithiocarbamates, Vinod K Tiwari,^* A Singh, H A Hussain, B B Mishra, V J Tripathi (2007, Tet Lett., manuscript under preparation).

(C) Books:

1. Tiwari V K, Singh Y (2007): Problems based on Reaction Mechanism, New Age International Publication, New Delhi (Under Process)

(D) Papers Presented at Symposia:

1.  Unexpected Isomerisation reaction with DBU: An easy access to a-alkylidene tetrahydrofuranose V K Tiwari and R P Tripathi, Current Trends in Drug Discovery Research (CTDDR), 11-15 Feb 2001 at Central Drug Research Institute, Lucknow.

 2. Antifilarial profile of a novel lead compound: 7-O- (4-methyl piperazin-acetyl)-4-methyl-2H-1- benzopyran-2-ones, R. P. Tripathi, V K Tiwari, S Bhattacharya, K Srivastava, V M L Srivastava and P K Murty, Indian Conference of Parasitology, 1-3 Oct 2001 at Jodhpur.

 3. Synthesis of glycosylated amino esters as DNA topoisomerase-II inhibitors A. R. Khan, R. P. Tripathi, V. K. Tiwari, R. C. Mishra, V. J. M. Reddy and J. K. Saxena, National Bio-Organic Symposium-7, Guru Nanak Deo University, Amritsar, 7-10 November 2001.

4. Depletion of Intracellular Glutathione of Setaria cervi by Dimethylmaleate, Phorone and Aminoalkane Derivatives, S Gupta, V K Tiwari, R P Tripathi, A K Sriwastava, Indian Conference of Parasitology, 1-3 October 2001 at Jodhpur.

 5. Glycosylated b-amino acids as a new class of antitubercular agents, V. K. Tiwari, R. P. Tripathi, R. Tripathi, L. Bala, S. Sinha, A. Srivastava, R. Srivastava, B. S. Srivastava, 16^th Carbohydrate Conference, 6-7 December 2001 at Central Tubercrop Research Institute, Trivendrum. (Oral presentation)

 6. Synthesis and bioevaluation of glycosyl ureas as a-glucosidase inhibitors and antituberculosis agents: V K Tiwari, N. Tewari, R. C. Mishra, R. P. Tripathi, A. K. Srivastava, R. Ahmad, R. Srivastava and B. S. Srivastava, International symposium on Drug Discovery and Process Research (DDPR), Shivaji University, Kolhapur, January 23-25, 2003.

 7. Combinatorial and conventional synthesis of glycohybrid molecules as new class of anti tubercular agents. V. K. Tiwari, R. P. Tripathi, V. Chaturvedi, A. Srivastava, S. Sinha, R. Srivastava, B S Srivastava, An international conference on Current trends in drug discovery research (CTDDR), 17-20 Feb 2004 at Central Drug Research Institute, Lucknow.

 8. Inhibitors of filarial g-glutamyl cycle enzymes as possible macrofilaricidal agents, S. Gupta, K. Arora, V K Tiwari, R P Tripathi, A. K. Srivastava, R D Walter, An international conference on Current trends in drug discovery research (CTDDR), 17-20 Feb 2004 at Central Drug Research Institute, Lucknow.

 9. Combinatorial synthesis of glycohybrid molecules as potential chemotheraupetic agents, R C Mishra, V. K. Tiwari, R. P. Tripathi, An international conference on Current trends in drug discovery research (CTDDR), 17-20 Feb 2004 at Central Drug Research Institute.

 10. Solid Phase Combinatorial Synthesis (SFCS) of glycosyl ureas as potential chemotherapeutic agents, V K Tiwari, N Tewari, R P Tripathi, B K Tripathi, A K Srivastava, An International Conference in Recent Advances In Biomedical and Therapeutic Sciences (ICRABTS), 13-15 Jan 2004, at Bundelkhand University, Jhansi. (Awarded Young Investigator prize and offer for post of lecturer by Hon’ble Vice Chancellor)

 13. Solid phase combinatorial synthesis of C-Nucleosides as a potential Chemotherapeutic agents, V. K Tiwari, R C Mishra, R P Tripathi, 41^st Annual convention of Chemists, 23-27 Dec 2004 to be held at New Delhi. (Awarded Dr D S Bhakuni Award-2004)

14. Synthesis and antitubercular activity of glycosyl sulphides and sulphones, V K Tiwari, RP Tripathi, 2^nd International conference on Recent Advances in Biomedical and Theraupetic Sciences (ICRABTS 2005), 5-8^th January 2005 at Bundelkhand University Jhansi.

 15.Synthesis and Bioevaluation of 2- (1’, 4’)-Phenylene-bis-5-Substituted Aryl Amino-[1,2,4] Thiadiazol-3-One, Vinay Kumar, D D Singh, R Trivedi, Virendra Prasad, Rajesh Dabur, R Singh, G L Sharma, V K Tiwari^* and Ramesh Chandra, 2^nd International conference on Recent Advances in Biomedical and Theraupetic Sciences, (ICRABTS 2005), 5-8^th January 2005 at Bundelkhand University Jhansi.

16. Conference attended in Abroad: VI^th Floheret Heterocyclic Conferences, 28^th Feb - 2^nd 2005, Department of Chemistry, University of Florida, USA.

17. Recent application of Electrophilic Amination, D D Singh, S K Dwivedi, R P Tripathi, V K Tiwari, Knowledge Exchange Programe in Life Science and Research (KEPLER) organized by Department of Biochemistry, J. C. Bose institute of Life Sciences, Bundelkhand University, Jhansi, 30 April-1 May, 2005.

18. Development of Carbohydrate Derivatives as Antituberculosis agents, V K Tiwari, R P Tripathi, Knowledge Exchange Programe in Life Science and Research (KEPLER) organized by Department of Biochemistry, J. C. Bose institute of Life Sciences, Bundelkhand University, Jhansi, 30 April-1 May, 2005 (Invited Lecture).

19. Screening and Selection of some Indian Medicinal Plants for Their Antimycotic Potential, Singh D D; Arif T; Agrawal R K; Dabur R; Tiwari V K: UP Micron-2006 at Medical college on Feb 11-12.2006.

20. Synthesis of Glycosyl Heterocycles as potential chemotheraupetic Agents, Tiwari V K and Tripathi R P:, International Conference on Molecules to Material (ICMM-06), 4-5^th March 2006 at Sant Longwal Institute of Technology and Science, Longowal Punjab.

21. Sustained Release Bi-Layered Tablets of Domperidone Maleate Using Hydrophilic Matrix System, Pandey H; Tiwari V K; Prajapati: has to be present in National Symposium on Designing the Molecular World Through Chemistry, at Department of Chemistry, Banaras Hindu University, March 22-24, 2006.

22. BENZOTRIAZOLE MEDIATED ONE POT CONVENIENT SYNTHESIS OF THIOQUINAZOLINONES AS POTENTIAL ANTIFUNGAL AGENTS, Vinod K Tiwari,^* H A Hussain, B B Mishra, D D Singh, V J Tripathi , Current Trendrs in Drug Discovery Research. (2007)

23. 7- Isovarleryloxy-8-methoxygirinimbine:Anew Carbazole alkaloid from Murraya koenigii  Bhuwan B. Mishra, Vinod K. Tiwari, D D Singh, Archana Singh, V J Tripathi ^* Current Trendrs in Drug Discovery Research (2007).

24. Benzotriazole mediated one pot convenient synthesis of Thioquinazolinones as potential Antifungal agents, Vinod K Tiwari,^* H A Hussain, B B Mishra, D D Singh, V J Tripath,  U P College, Varanasi (2006).

25. Benzotriazole mediated one pot convenient and new synthesis of Glycosyl Dithiocarbamates, Vinod K. Tiwari^*, Archana Singh, B B. Mishra, V J Tripathi, at U P College, Varanasi (2006)

26. Benzotriazole mediated one pot convenient and new synthesis of diverse Dithiocarbamates, Vinod K. Tiwari^*, Archana Singh, H A Hussain, B B. Mishra, V J Tripathi, ICC, 2006 at Birla college of Science, Kalyan, Bombay.