Dr. Arvind Kumar

Associate Professor
Ph D (BHU)
Contact Information:
Tel: (O); 2368331; 6701584;Fax: 2368693
Email Id:k_arvindk@rediffmail.com

 
Academic Qualifications:
 
S. No.DegreeInstitutionYear
1.B.Sc.Magadh University1987
2.M.Sc.Patna University1991
3.Ph. D.Banaras Hindu University1999
 
 
Brief writeup on area of specialization/awards/achievements:
 

Molecular Biology and Immunology: Role of transcription factors (TFs) and their ability to talk to each other to regulate the cytokine genes. Study of expression and possible role of inflammatory / non-inflammatory cytokines in the liver and lungs cancer in mice model. Immunomodulatory role of selected herbal plants in cancerous mice model. Finding will help to understand the mechanism at molecular level to use the genes/herbs for therapeutic purposes. Our current research focuses on two main areas of research

  1. Molecular basis of cytokines and chemokines gene regulation and their role in immunity/cancer disease.
  2. Immunomodulatory role of certain herbs and chemicals.
  3. Find out new therapeutic genes and their use for therapeutic purposes.
  4. Signal transduction
Awards:
  1. National merit Scholarship (during I.Sc., B.Sc.)
  2. UGC-Junior/Senior Research Fellowship award (during Ph.D.)
  3. Post-doctoral Fellowship in NIH project at Baylor College of Medicine/University of Pittsburgh, USA.

 
Projects continuing as PI/ Co PI:
 

One project is submitted to DBT as PI
 
Any additional information:
 
  • April 2005 to Oct. 2005 Research Associate - Department of Transplantation Pathology, University of Pittsburgh Medical Center (UPMC); Biomedical Science Tower, University of Pittsburgh, PA 15261, USA.
  • March 2002 to March 2005 Research Associate - Dept. of Mol. Gen. and Biochem., School of Medicine, E-1240, Biomedical Science Tower, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Oct. 2001 to March 2002 Postdoctoral Fellow - Dept. of Environmental Science, Birmingham, School of Public Health, University of Alabama at Birmingham, Ryales Bldg. 1665 Univ. Blvd. AL 35294, USA.
  • Sep. 2000 to Oct. 2001 Postdoctoral Fellow - Center for Cell and Gene Therapy, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77054, USA.

List of 10 major Publications:

  1. Arvind Kumar, Santosh Kr. Singh, T.D. Singh, Satyaprakash (2009); "Methods, potentials and limitations of gene delivery to regenerate neuronal cells", Biologics: Targets & Therapy 2: 245-256 (Review). http://www.dovepress.com/methods-potentials-and-limitations-of-gene-delivery-to-regenerate-cent-peer-reviewed-article
  2. S. Unlu, S. Unlu, Arvind Kumar, W.R. Waterman, J. Tsukada, Kent Z.Q. Wang, D. L. Galson, Philip E. Auron (2007). Phosphorylation of IRF8 in a pre-associated complex with Spi-1/PU.1 and non-phosphorylated Stat1 is critical for LPS induction of the IL1B gene. Molecular Immunology 44: 3364-79.
  3. Yasuhiro Yoshida, Arvind Kumar, Yoshinobu Koyama, Haibing Peng, Ahmet Arman, Jason A. Boch, and Philip E. Auron (2003). IL-1 Activates Stat3/NFkB Cross-talk via Unique TRAF6 and p65 Dependent Mechanism. J. Biol. Chem. 279 (3): 1768-1776.
  4. Arvind Kumar, Linglong Zou, Xiaoqing Yuan, Long Yuan, Keyi Yang (2002) N-methyl-D-aspartate receptors: Transient loss of NR1/NRA/NR2B subunits after traumatic brain injury in a rodent model. J. Neuro Sci. Res. 67(6):781-786.
  5. L. Zou, Arvind Kumar, X. Yuan, J. Hannay, D. Shine and K. Yang (2001). Improvement of Cognitive Function and Cholinergic Neuron Transmission by Adenovirus-Mediated Nerve Growth Factor Gene Transfer in Aged Rat Brain. Molecular Therapy 3: S125-S126.
  6. D. P. Singh, M. B. Tyagi, Arvind Kumar, J. K. Thakur and Ashok Kumar (2000). Antialgal property of a hepatotoxin-producing cyanobacterium Microcystis aeruginosa. World J. Microbiol. Biotechnol. 17(1):15-22.
  7. Ashok Kumar, D.P.Singh, M.B. Tyagi, Arvind Kumar, E.G.Prasuna and J.K.Thakur (2000). Production of hepatotoxin by the cyanobacterium Scytonema sp. strain BT 23. J. Microbiol. Biotechnol. 10 (3): 375-380.
  8. Madhubala Tayagi, J. K. Thakur, D. P. Singh, Arvind Kumar, E.G. Prasuna and Ashok Kumar (1999). Cyanobacterial Toxins: The Current Status. J. Microbiol. Biotechnol. 9: 9-21
  9. Kusum Lata Singh, Arvind Kumar and Ashok Kumar (1998). Bacillus cereus capable of degrading SDS shows growth with a variety of detergents. World J. Microbiol. Biotechnol. 14: 777-779.
  10. Arvind Kumar and Ashok Kumar (1998). Isolation of Pseudomonas aeruginosa strain capable of degrading acrylamide. J. Microbiol. Biotechnol. 8: 347-352.
    Others publication:
    Abstract/paper presented and published in National/International Seminar:
  11. Shalini Verma, Chandradeo Narayan and Arvind Kumar (2009). Anti-cancerous properties of natural growing herbs or medicinal plants to regulate cancerous and anti-cancerous genes. International conference on recent trends in life sciences researches vis a vis natural resource management sustainable development and human welfare. June 27-29, 2009 at VBU, Haz. (Abstract p-251).
  12. Chandradeo Narayan and Arvind Kumar (2009). Activation of NFkB & STAT3 promotes urethane-induced lung carcinogenesis in mice model. XXXIII all India Cell biology conference and International workshop on cell cycle regulation (AICBC-2009) at Hydrabad (Abstract P-143).
  13. Shalini Verma and Arvind Kumar (2009). Up regulation of pro-inflammatory cytokines in response to N-nitroso-N-methyl Urea induced cancerous liver of mice (balb/C). International symposium on caner chemoprevention and translational research Dec. 21 2009 at JNU (Abstract p-34).
    Chapters contributed to books:
  1. D. P. Singh, M.B. Tyagi, Arvind Kumar, E.G. Prasuna, G. Srinivas, and Ashok Kumar (2000). Bioactive Secondary Metabolites From Cyanobacteria,.Festschrift.
  2. Arvind Kumar (2008). Gene, Gene expression and Gene regulation (under revision).