Dr. Arvind Kumar

Professor & Coordinator
Ph.D. (BHU)
Contact Information:
Tel: +91 542 2368364; +91 9473875706Fax: +91 542 2368693
Email Id:arvindkumararvind8@gmail.com; k_arvindk@rediffmail.com; arvindk@bhu.ac.in

 
Academic Qualifications:
 
S. No.DegreeInstitutionYear
1.B.Sc.Magadh University1987
2.M.Sc.Patna University1991
3.Ph. D.Banaras Hindu University1999
 
 
Professional Employments:

S. No.Name of the Post Name of the DepartmentName of the Inst./UnivDuration
8. ProfessorSchool of BiotechnologyBanaras Hindu University (India)2012-Present
7. Associate ProfessorSchool of BiotechnologyBanaras Hindu University (India)2009-2012
6. ReaderSchool of BiotechnologyBanaras Hindu University (India)2005-2009
5. Research AssociateDepartment of Transplantation PathologyUniversity of Pittsburgh (USA)2005-2005
4. Research AssociateDepartment of Mol. Gen. and BiochemistryUniversity of Pittsburgh (USA)2002-2005
3.Visiting ScientistDepartment of Enviromnmental ScienceUniversity of Albama at Birmingham (USA)2001-2002
2.Post doctoral fellowDepartment of NeurosurgeryBaylor College of Medicine(USA)2000-2001
1.Post Doctoral FellowSchool of BiotechnologyBanaras Hindu University (India)1999-2000

 
Area of specialization/awards/achievements:
 

Molecular Biology and Immunology: Role of transcription factors (TFs) and their ability to talk to each other to regulate the cytokine genes. Study of expression and possible role of inflammatory / non-inflammatory cytokines in the liver and lungs cancer in mice model. Immunomodulatory role of selected herbal plants in cancerous mice model. Finding will help to understand the mechanism at molecular level to use the genes/herbs for therapeutic purposes.
Our current research focuses on two main areas of research

  1. Molecular basis of cytokines and chemokines gene regulation and their role in immunity/cancer disease.
  2. Immunomodulatory role of certain herbs and chemicals.
  3. Find out new therapeutic genes and their use for therapeutic purposes.
  4. Signal transduction
Awards/Patents filed:
  1. Arvind Kumar & Alok Tripathi: Chlorogenic acid (CGA) binds to HMGB-1 to enhance anticancerous capability of herbal extract against liver cancer, with name of investigations Anti-cancerous enhancement by CGA to cure liver cancer by binding to HMGB-1. Date of filing 06/05.2014. Docket NO. 11431. Application No. 1220/DEL/2014.
  2. National merit Scholarship (during I.Sc., B.Sc.)
  3. UGC-Junior/Senior Research Fellowship award (during Ph.D.)
  4. Post-doctoral Fellowship in NIH project at Baylor College of Medicine/University of Pittsburgh, USA.
 

List of 10 major Publications:

  1. 1. Somya Asthana, Sumita Dixit, Anshuman Srivastava, Arvind Kumar, Sheelendra P. Singh, Anurag Tripathi, Mukul Das (2019). Methylenecyclopropyl glycine, not pesticide exposure as the primary etiological factor underlying hypoglycemic encephalopathy in Muzaffarpur, India. Toxicology Letters; Vol. 301, Feb. 2019, 34-41 IF:3.166; Citations:00
  2. 2. Ashish Yadav, Arvind Kumar, M. Das, A. Tripathi (2016). Sodium benzoate, a food preservative, affects the functional and activation status of splenocytes at non cytotoxic dose. Food and Chemical Toxicology, 88, 40-47. IF:3.977, Citation:15
  3. 3. Arvind Kumar, Sarika Kumari, Alok Tripathi (2015). Toxicity evaluation of pH dependent stable Achyranthes aspera herbal gold nanoparticles. Applied Nanoscience. DOI: 10.1007/s13204-015-0414-x. Online First Articles ISSN: 2190-5509 (Print) 2190-5517 (Online) IF: 3.45, Citations:10
  4. 4. Chandradeo Narayan, Arvind Kumar (2014). Antineoplastic and immunomodulatory effect of polyphenolic components of Achyranthes aspera (PCA) on urethane induced lung cancer in vivo". Molecular Biology Reports. 41(1), 179-191. IF: 1.698; Citations: 13
  5. 5. Shalini Verma, Theeshan Bahorune, Ranjan Kumar Singh, Okezie I. Aruomae, Arvind Kumar (2013). Effect of Aegle marmelos leaf extract on N-methyl N-nitrosourea induced hepatocarcinogensis in Balb/c mice. Pharmaceutical biology. 51, 10: 1272-1281. IF: 1.546; Citations: 13
  6. 6. Chandradeo Narayan, Arvind Kumar (2012). Constitutive expression of IL-1, IL-6, NF-?B and Stat3 is a potential cause of lung tumorgenesis in urethane (ethyl carbamate) induced Balb/c mice. Journal of Carcinogenesis. 11:9. 0974.6773. IF: 3.81 (RG); Citations: 27.
  7. 7. Shalinin Verma, T. Bahorun, Arvind Kumar (2012). N-methyl N-nitroso Urea induced altered DNA structure initiate hepatocarcinogenesis. Preventive Medicine. Vol 54 (1) S130-S136. IF: 2.47; Citaions:11
  8. 8. Ashish Yadav, Arvind Kumar, Premendra Dhar Dwivedi, Anurag Tripathi, Mukul Das (2012). In vitro studies on immunotoxic potential of Orange II in splenocytes. Toxicology Letters. 208 (3) 239-245. IF: 3.522; Citations:33
  9. 9. Yasuhiro Yoshida, Arvind Kumar, Yoshinobu Koyama, Haibing Peng, Ahmet Arman, Jason A. Boch, and Philip E. Auron (2004). IL-1 Activates Stat3/NFkB Cross-talk via Unique TRAF6 and p65 Dependent Mechanism. J. Bio. Chem. 279 (3): 1768-1776. IF:4.01; Citation: 132
  10. 10. Arvind Kumar, Linglong Zou, Xiaoqing Yuan, Long Yuan, Keyi Yang (2002) N-methyl-D-aspartate receptors: Transient loss of NR1/NRA/NR2B subunits after traumatic brain injury in a rodent model. J. Neuro Sci. Res. 67(6):781-786. IF: 2.66; Citation: 105
    Full List of Publications:
    A. Research papers published in International Journal of repute:
  11. 27. Somya Asthana, Sumita Dixit, Anshuman Srivastava, Arvind Kumar, Sheelendra P. Singh, Anurag Tripathi, Mukul Das (2019). Methylenecyclopropyl glycine, not pesticide exposure as the primary etiological factor underlying hypoglycemic encephalopathy in Muzaffarpur, India. Toxicology Letters; Vol. 301, Feb. 2019, 34-41 https://doi.org/10.1016/j.toxlet.2018.10.033 IF:3.166
  12. 26. Prashant Gupta, Alok Tripathi, Trapti Agrawal, Chandradeo Narayan, BM Singh, Mohan Kumar, Arvind Kumar (Aug, 2016). Synergistic protective effect of picrorhiza with honey in acetaminophen induced hepatic injury. Indian Journal of Experimental Biology. 54:530-536. IF: 1.165
  13. 25. Prashant Gupta, Brij Mohan Singh, Trapti Agrawal, Arvind Kumar (Jun, 2015). Clinical evaluation of potentiating effect of honey and mandur bhasma (herbo-mineral preparation) in anemic children. World Journal of Pharmaceutical Sciences. 3 (6) 1173-1179. (ISSN (print): 2321-3310; ISSN (online):2321-3086. Atom and Cell Publishers. http://www.wjpsonline.org/admin/uploads/4mAwFn.pdf IF: 0.453
  14. 24. Arvind Kumar, Sarika Kumari, Alok Tripathi (2015). Toxicity evaluation of pH dependent stable Achyranthes aspera herbal gold nanoparticles. Applied Nanoscience. DOI: 10.1007/s13204-015-0414-x. Online First Articles ISSN: 2190-5509 (Print) 2190-5517 (Online) IF: 3.45
  15. 23. Arvind Kumar, Alok Tripathi, Sushil Dawka, Arun Kumar Agnihotri (2014). Cytokines in the interface of metabolomics based cancer and type-2 diabetes. Archives of Medical and Biomedical Research. 1(3) 113-120. IF:
  16. 22. Chandradeo Narayan, Arvind Kumar (2014). Antineoplastic and immunomodulatory effect of polyphenolic components of Achyranthes aspera (PCA) on urethane induced lung cancer in vivo. Molecular Biology Reports. 41(1), 179-191. IF: 1.698
  17. 21. Shalini Verma, Theeshan Bahorune, Ranjan Kumar Singh, Okezie I. Aruomae, Arvind Kumar (2013). Effect of Aegle marmelos leaf extract on N-methyl N-nitrosourea induced hepatocarcinogensis in Balb/c mice. Pharmaceutical biology. 51, 10: 1272-1281. IF: 1.546
  18. 20. Ashish Yadav, Arvind Kumar, Anurag Tripathi, Mukul Das (2013). Sunset yellow FCF, a permitted food dye, alters functional responses of splenocytes at non-cytotoxic dose. Toxicology Letter. Vol 217, Issue 3 Pages 197-204. IF: 3.522
  19. 19. Chandradeo Narayan, Arvind Kumar (2013). Identification and characterization of phenolic compounds in hydro methanolic extract of Achyranthes aspera (HMEA) by UPLC and MALDI-TOF-MS and in vivo antioxidant activity. Oriental Pharmacy and Experimental Medicine. 13 (1) 51-59. IF: 0.73
  20. 18. Suchitra Kamle, A. Ojha, Arvind Kumar (2012). Safety assessment of Cry2AB protein in genetically modified crops: Digestibility assay and IgE evaluation. Journal of Clinical immunology. 32 (1) 232-233. IF: 3.094
  21. 17. Chandradeo Narayan, Arvind Kumar (2012). Constitutive expression of IL-1, IL-6, NF-?B and Stat3 is a potential cause of lung tumorgenesis in urethane (ethyl carbamate) induced Balb/c mice. Journal of Carcinogenesis. 11:9. 0974.6773. IF: 3.81 (RG)
  22. 16. Chandradeo Narayan, Arvind Kumar (2012). Carcinogenicity and Immunological effects of urethane present in various food products in vivo. Conference Full Proceeding. National Conference on Biotechnology and Biodiversity March 13th and 14th Dept. of Botany and Biotechnology Govt. New Science College, Rewa, M.P. Pp37-45. IF:
  23. 15. Shalinin Verma, T. Bahorun, Arvind Kumar (2012). N-methyl N-nitroso Urea induced altered DNA structure initiate hepatocarcinogenesis. Preventive Medicine. Vol 54 (1) S130-S136. IF: 2.47
  24. 14. Ashish Yadav, Arvind Kumar, Premendra Dhar Dwivedi, Anurag Tripathi, Mukul Das (2012). In vitro studies on immunotoxic potential of Orange II in splenocytes. Toxicology Letters. 208 (3) 239-245. IF: 3.522
  25. 13. Suchitra Kamle, A. Ojha, Arvind Kumar (2011). Development of an enzyme linked immune sorbent assay for the detection of Cry2Ab protein in transgenic plants. G. M. Crops. (Vol 2, Issue 2). IF: 1.76 (RG)
  26. 12. Suchitra Kamle, Arvind Kumar, Raj K. Bhatnagar (2011). Development of multiplex and construct specific PCR assay for detection of cry2Ab transgene in genetically modified crops and product. G.M. Crops. 2:1, 1-8. IF: 1.76 (RG)
  27. 11. Arvind Kumar, Santosh Kr. Singh, T.D. Singh, Satyaprakash (2009); "Methods, potentials and limitations of gene delivery to regenerate neuronal cells", Biologics: Targets & Therapy 2: 245-256 (Review). ISSN: 1177-5491 (Online); ISSN: 1177-5475. IF: 2.70 (RG)
  28. 10. S. Unlu, Arvind Kumar, W.R. Waterman, J. Tsukada, Kent Z.Q. Wang, D. L. Galson, Philip E. Auron (2007). Phosphorylation of IRF8 in a pre-associated complex with Spi-1/PU.1 and non-phosphorylated Stat1 is critical for LPS induction of the IL1B gene. Molecular Immunology. 44(13): 3364-79. http://www.ncbi.nlm.nih.gov/pubmed/17386941. ). IF 2.916 Citation: 19
  29. 9. Unlu, S; Kumar, Arvind; Galson, DL; Auron, P E. (2006). A complex involving IRF8, Spi-1 and non-tyrosine-phosphorylated Stat1 is essential for induction of human IL-1 gene transcription. The Journal of the Federation of American Societies for Experimental Biology (FASEB JOURNAL). 20 (5): A1344-A1344. IF 5.712.
  30. 8. Yasuhiro Yoshida, Arvind Kumar, Yoshinobu Koyama, Haibing Peng, Ahmet Arman, Jason A. Boch, and Philip E. Auron (2004). IL-1 Activates Stat3/NFkB Cross-talk via Unique TRAF6 and p65 Dependent Mechanism. J. Bio. Chem. 279 (3): 1768-1776. http://www.ncbi.nlm.nih.gov/pubmed/14593105. Citation: 83
  31. 7. Arvind Kumar, Linglong Zou, Xiaoqing Yuan, Long Yuan, Keyi Yang (2002) N-methyl-D-aspartate receptors: Transient loss of NR1/NRA/NR2B subunits after traumatic brain injury in a rodent model. J. Neuro Sci. Res. 67(6):781-786. http://www3.interscience.wiley.com/journal/90512386/abstract. Citation: 56
  32. 6. L. Zou, Arvind Kumar, X. Yuan, J. Hannay, D. Shine, K. Yang (2001). Improvement of Cognitive Function and Cholinergic Neuron Transmission by Adenovirus-Mediated Nerve Growth Factor Gene Transfer in Aged Rat Brain. Molecular Therapy 3(5): S125-S126.
  33. 5. D. P. Singh, M. B. Tyagi, Arvind Kumar, J. K. Thakur, Ashok Kumar (2000). Antialgal property of a hepatotoxin-producing cyanobacterium Microcystis aeruginosa. World-J. Microbiol. Biotechnol. 17(1):15-22. Citation: 71
  34. 4. Ashok Kumar, D.P.Singh, M.B. Tyagi, Arvind Kumar, E.G.Prasuna and J.K.Thakur (2000). Production of hepatotoxin by the cyanobacterium Scytonema sp. strain BT 23. J. Microbiol. Biotechnol 10 (3) : 375-380. Citation: 4
  35. 3. Madhubala Tayagi, J. K. Thakur, D. P. Singh, Arvind kumar, E.G. Prasuna, Ashok Kumar (1999). Cyanobacterial Toxins: The Current Status. J. Microbiol. Biotechnol. 9: 9-21 (Review). Citation: 26
  36. 2. Kusum Lata Singh, Arvind Kumar, Ashok Kumar (1998). Short communication: Bacillus cereus capable of degrading SDS shows growth with a variety of detergents. World-J. Microbiol Biotechnol. 14: 777-779. Citation: 11
  37. 1. Arvind Kumar, Ashok Kumar (1998). Isolation of Pseudomonas aeruginosa strain capable of degrading acrylamide. J. Microbiol Biotechnol 8: 347-352. Citation: 3
    B. Books and Chapters in Book:
  1. Arvind Kumar (2013). Text book of Immunology from TERI (Internatinoal press & publisher).
  2. Suchitra Kamle, Dawei Li, Abhishek Ojha, Arvind Kumar (2019). Development of an Enzyme-Linked Immunosorbent Assay for the detection of GM proteins in transgenic crops/produce: in Methods and Protocols.
  3. Methylene-Cyclo-Propyl Glycine in Sapindaceae Family by S. Asthana, A. Tripathi, P.D. Dwivedi, Arvind Kumar, and M Das (2018). In Book Production and Protection of Horticultural Crops (K.V. Peter) ISBN:9789386546418. New Delhi publishing agency.
  4. S. Asthana, A. Tripathi, P.D. Dwivedi, A. Kumar and M. Das (2017). Chapter Methylene-Cyclo-Propyl Glycine in Sapindaceae. Book: Production and protection of horticultural crops by K.V. Peter ISBN: 9789386546418. Publisher: New India Publishing Agency (NIPA), New Delhi- 110088.
  5. Arvind Kumar (2013). Aushdhiye paudho kee viagyanik pramanikta (Scientific proof of medicinal plants) article in Hindi. Vigyan Ganga p48-50 (ISSN 2331-2455) Publisher: Hindi Prakashan Samiti, BHU, Varanasi.
  6. Suchitra Kamle, A. Ojha, Arvind Kumar (2013). Development of Enzyme linked Immunosorbant (ELISA) Assay for the detection of Bt-protein in transgenic cotton. Transgenic Cotton: Methods in Molecular Biology; Vol 958, page 131-138. (ISSN 978-1-62703-211-7) Springer.
  7. Arvind Kumar (2008). Gene: Expression and Regulation. Recent Advances in Life Sciences. Chapter-16: 353-381, IK international publisher. (ISSN 978-93-81141-04-5)
  8. Singh,D.P., Tyagi,M.B., Kumar A., Prasuna E.G. and Kumar Ashok (2002). Bioactive secondary metabolites from cyanobacteria pp275-292, In: The Algological Research in India Volume-3rd. Festschrift to Prof. V N Raja Rao Edited by Prof. Anand, N.) Charok (ID 886143) Dehra Dun Bishen Singh and Mahendra Pal Singh. (ISBN: 10: 8121102081 9788121102087)
    C. Talks delivered/presented in Conferences/workshops/symposiums :
  9. Speaker & Chaired session in International Symposium on Tumor Microenvironment and Cancer Prevention & Therapeutics being organized by the Jawaharlal Nehru University (JNU), New Delhi, India during 08-09 February 2019 entitled Lung Cancer Genesis Microenvironment formation by ethyl carbamate and mitigation of cancer by Achyranthes aspera extract
  10. Invited talk entitled Bioinformatics & Its application in Modern Science development. In Bioinformatics Workshop organized by Aagrasen Kanaya PG College, Varanasi 16 Feb. 2018
  11. Invited talk entitled Revelation of new targeting molecule for cancer therapy. International symposium on cancer prevention and treatment Feb, 9-10, 2018 at School of Life Sceiences, JNU, New Delhi, India
  12. Invited talk entitled Modern general biotechnology in relation with food science technology. Seminar cum workshop organized by Center of Food Science and Technology, Institute of Agriculture Sciences, BHU, Varanasi 25 Oct 2017
  13. Invited talk entitled Food Science Food Commodities Dye And Its Immunomodulatory Effects. Seminar cum workshop organized by Center of Food Science and Technology, Institute of Agriculture Sciences, BHU, Varanasi 9 Nov 2017
  14. Convener of 1day seminar and 6-day workshop on Genes to Genomics, a current status from 1st March to 7th march, 2017.
  15. Given invited talk in International conference Persepectives on modern india and the emerging world order:old issues and new challenges held between 20-21 Feb, 2016 at BHU, Institute of Science, seminar hall on topic entitled Technology-Economy interface problems and prospects for India on 21 Feb. 2016.
  16. Invited talk has been given on the topic entitle Carcinogenicity and Immunological effects of urethane present in various food products in vivo. National Conference on Biotechnology and Biodiversity Biological Resources Conservation, Management and Sustainable Uses 13-14th March 2012, at Govt. M.S. Golwalkar College, Rewa (M.P.), India.
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