Dr. S.M. Singh

Professor
Ph D (BHU)
Contact Information:
Tel: (O); 0542-2368331 Fax: 0542-2368693
Email Id:sukhmahendrasingh@yahoo.com

 
 
Academic Qualifications:
 
S. No.DegreeInstitutionYear
1.High School U.P. Board of Education1976
2.IntermediateU.P. Board of Education1978
3.B.Sc.Banaras Hindu University1982
4.M.Sc.Banaras Hindu University1985
5.Ph. D.Banaras Hindu University1988
 
Brief writeup on area of specialization/awards/achievements:
 

Tumor Immunology. Our current research focuses on two main areas of research
Tumor-specific metabolism.
Screening of drugs for antitumor activity.
Targeting Tumor microenvironment for therapy.
Tumor-associated immunosuppression: host-tumor interaction.
Tumor immunotherapy (cell therapy; immunomodulation)
Gender, stage and behavior dependent variation in Tumor growth.
Neuroendocrine regulation of tumor growth.
Immuno-senescence and cancer.
Awards/achievements:

  • 1990 Indian National Science Academy Medal for Young Scientists (INSA Young Scientists Medal)
  • 1990 Prof. L.S.S. Kumar Memorial Award, INSA, New Delhi
  • 1982 Banaras Hindu University Prize For securing First position in order of merit in Zoology Honours in B.Sc.Exam
  • 1985 Banaras Hindu University Medal for securing First position in the order of merit in M.Sc. Examination
  • 1985 Ramakrishna Memorial Reddy Award for securing highest marks in Biochemistry in M.Sc.
  • 2000 Alexander von Humboldt Fellowship
  • 1988 Monbusho (Japanese Government Fellowship)
  • 1999 Fiscal Research Fellowship (Japanese Government Fellowship)
  • Member: Editorial Board.
    1. BHU journal of Science (BHU Press)
    2. Oriental pharmacy and experimental medicine (KHU Press)
    3. Lymphoma (Handawi-Sage Publication)
    Member: Societies
    1. Indian Cell Biology Association
    2. Indian Cancer Society
 
Research Projects:
 

  1. 'Targeting of the Bioactive Molecule Hapalindole T isolated from cyanobacterium Fischerella sp.' sanctioned by Department of Science and Technology, New Delhi (23 Lakhs)
  2. 'Mission Mode project on hydrogen production through biological routes' by Ministry of Non Renewable Energy, New Delhi (33 Lakhs).
 
Any additional information:
 

List of Select Publications:

  1. Verma VK, Singh V, Singh MP, Singh SM. Treadmill exercise-dependent tumor growth retardation in T-cell lymphoma-bearing host displays gender dimorphism. Oncol Res. 2010;18(7):293-304. PubMed PMID: 20377130.
  2. Singh V, Singh SM. Progressive tumor growth-associated altered tumor microenvironment: implications in a tumor stage-dependent modulation in survival of a murine T cell lymphoma. J Cancer Res Clin Oncol. 2009 Aug;135(8):1015-24.Epub 2009 Jan 6. PubMed PMID: 19125295.
  3. Singh V, Singh SM. A tumour stage-dependent evolution of drug resistant T cell lymphoma: role of soluble mediators of tumour and host origin. Leuk Res. 2009 May;33(5):700-9. Epub 2008 Oct 18. PubMed PMID: 18930317.
  4. Gupta V, Singh SM. Gender dimorphism of macrophage response to GMCSF and IL-4 for differentiation into dendritic cells. Am J Reprod Immunol. 2008 Jul;60(1):43-54. PubMed PMID: 18593437.
  5. Shrivastav Anuraag; Varma Shailly; Lawman Zoe; Yang Shao H; Ritchie Shawn A; Bonham Keith; Singh Sukh M; Saxena Anurag; Sharma Rajendra K. Requirement of N-myristoyltransferase 1 in the development of monocytic lineage. Journal of immunology (Baltimore, Md.: 1950) 2008;180(2):1019-28.
  6. Singh MP, Sharma H, Singh SM. Prolactin promotes growth of a spontaneous T cell lymphoma: role of tumor and host derived cytokines. Cancer Invest. 2006 Oct;24(6):601-10. PubMed PMID: 16982465.
  7. Shrivastava, P., Singh, S.M., Singh, N. (2004). Activation of tumor associated macrophages by thymosin a1. Int. J. Immunopathol. Pharmacol. 17, 39-48.
  8. Bharti AC, Singh SM. Inhibition of macrophage nitric oxide production by gangliosides derived from a spontaneous T cell lymphoma: the involved mechanisms. Nitric Oxide. 2003 Feb;8(1):75-82. PubMed PMID: 12586545.
  9. Bharti A C; Singh S M. Induction of apoptosis in bone marrow cells by gangliosides produced by a T cell lymphoma. Immunology letters 2000;72(1):39-48.
  10. Parajuli P; Nishioka Y; Nishimura N; Singh S M; Hanibuchi M; Nokihara H; Yanagawa H; Sone S. Cytolysis of human dendritic cells by autologous lymphokine-activated killer cells: participation of both T cells and NK cells in the killing. Journal of leukocyte biology 1999;65(6):764-70.
Chapters contributed to books:
  1. Singh SM, Singh N, Singh V. Immunomodulatory and antitumor actions of Tinospora cordifolia (Guduchi). Natural Products Chemistry, Biochemistry and Pharmacology. Brahmachari G, (Ed). Narosa Publishing House, India. 2009 pp 114-136.
  2. Gupta V, Singh SM. Role of hormonal and cytokine environment of tumor-bearing host in manifestation of gender dimorphism of tumor growth. Treatment of advanced stage cancers. Talwar GP, Sood OP (Eds). Narosa Publishing House, India. 2009 pp 191-208.
  3. Vishvakarma NK, Shrivastava P, Singh SM.Thymic Peptides : Hormones with Biological Response Modifying Potential and Multi-Utility Therapeutic Applications in Life Threatening Pathologies. Editors: Singh MP, Agrawal A, Sharma B (Eds). 2009. 13TH Chapter.
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