Muniyandi Singaravel

Associate Professor
Ph.D. (Madurai Kamraj Univ)
Contact Information:

(O)0542-6701819(Lab); Cell: 09450574137     Fax:0542-2368457
Email Id: Email Id:m_singaravel@yahoo.com

 
Academic Qualifications:
 
S. No.DegreeInstitutionYear
1.B.Sc.Madurai Kamraj University 1988
2.M.Sc.Madurai Kamraj University1991
3.M.Phil.Madurai Kamraj University1992
4.Ph. D.Madurai Kamraj University1999
 
Brief writeup on area of specialization/awards/achievements:
 

We aim to study different aspects of the circadian clock; from behavior to genes related to phase re-setting by using photic and non-photic cues. The effects of certain different wavelengths of light and centrally active compounds on the circadian locomotor activity rhythm in nocturnal as well as diurnal mammals are currently being elucidated at our facility. We have also collaborated with scientists of various disciplines in order to address the circadian aspects of various research problems. The outcome of study from our lab will help to treat the patients of circadian rhythm disorders due to shift work, jet-lag or other environmental factors.

 
DISTINCTIONS/ PRIZE/ MEDAL/ AWARD/ HONOURS :
 

  • Senior Research Fellowship awarded by the CSIR, Government of India – 1996
  • JSPS Post Doctoral Fellowship Award awarded by the Government of Japan, 2001-2003.
  • Organizing Secretary, XVII National Symposium on Chronobiology, Department of Zoology, Banaras Hindu University, Varanasi, from 01.10.2005 to 03.10.2005.
 
 
 
 
Current Project Undertaken as PI/ Co PI:
 
S. No. Name of the Project Duration Source of Funding Amount of Funding (Rs) Any other Information
1. Effect of a serotonin antagonist on the circadian clock in the Indian pygmy field mouse, Mus booduga (P.I) 2011-2013 UGC-
2. Effect of withanolide on chronic circadian rhythm disruption-induced cognitive deficit in mice (P.I) 2013-2016 DST(CSI)-
 

List of 10 major Publications:

  1. P. Basu and M. Singaravel (2013). 5-hydroxy-l-tryptophan entrains the free-running rhythm in constant darkness in pygmy mice. Biological Rhythm Research (Accepted; Ref. BRR86WJR12; dated 19.01.2013).
  2. P. Basu and M. Singaravel (2013). Acceleration of re-entrainment during a 6-h acute jet lag simulation by 5-hydroxy-l-tryptophan in pygmy field mice. Biological Rhythm Research (Accepted; DOI:10.1080/09291016.2013.770294).
  3. P. Basu and M. Singaravel (2012). Potentiation of light-induced phase shifts by 5-hydroxy-L-trptophan in pygmy field mice: a preliminary report. Biological Rhythm Research (Accepted; Ref. No. BRR52WJR12; ID: 730889; DOI:10.1080/09291016. 2012. 730889).
  4. P. Basu and M. Singaravel (2012). Accurate and precise circadian locomotor activity rhythms in male and female Indian pygmy field mice, Mus terricolor. Biological Rhythm Research, DOI:10.1080/09291016.2012.721587.
  5. P. Basu, M. Singaravel and C. Haldar (2012). L-5-hydroxytryptophan resets the circadian locomotor activity rhythm of the nocturnal Indian pygmy field mouse, Mus terricolor. Naturwissenschaften 99:233-239; DOI 10.1007/s00114-012-0893-5.
  6. P. Basu, R. Tripathi, R. Mishra and M. Singaravel (2012). Effect of Chronic jet lag after induction of Dalton’s Lymphoma in male and female mice. Biological rhythm Research 43:3, 331-339 (DOI:10.1080/09291016.2011.579756).
  7. M. Singaravel, Fujisawa, Y., Hisada, M., Saifullah, A. S. M. and Tomioka, K. (2003). Phase shifts of the circadian locomotor rhythm induced by pigment-dispersing factor in the cricket Gryllus bimaculatus. Zoological Science 20: 1347-1354.
  8. V. K. Sharma, M. K. Chandrashekaran, M. Singaravel and R. Subbaraj (1999). Relationship between light intensity and phase resetting in a mammalian circadian system. Journal of Experimental Zoology., 283: 181-185.
  9. V. K. Sharma, M. K. Chandrashekaran, M. Singaravel and R. Subbaraj (1999). In the field mouse Mus booduga melatonin phase response curves (PRCs) have a different time course and waveform relative to light PRC. Journal of Pineal Research., 26(3): 153-158.
  10. V. K. Sharma, M. Singaravel, R. Subbaraj and M. K. Chandrashekaran (1999). Timely administration of melatonin accelerates re-entrainment to phase shifted light dark cycles in the field mouse Mus booduga. Chronobiology International., 16(2): 163-170.

A. Full list of Publications:

  1. 1. M. Singaravel, V. K. Sharma, R. Subbaraj and N. G. Nair (1996). Chronobiotic effect of melatonin following phase shift to light/ dark cycles in the field mouse Mus booduga. Journal of Biosciences., 21(6): 789-795.
  2. R. Subbaraj, J. Balasingh and M. Singaravel (1996). Observations on the post-natal development of Indian false vampire bat Megaderma lyra (Microchiroptera). Journal of Bombay Natural History Society., 94(2): 350-355.
  3. V. K. Sharma, M. Singaravel, M. K. Chandrashekaran and R. Subbaraj (1997). Relationship between free-running period and minimum tolerable light pulse interval of skeleton photoperiods in field mice Mus booduga. Chronobiology International., 14(3): 237-245.
  4. V. K. Sharma, M. Singaravel and M. K. Chandrashekaran (1998). Period dependent oscillatory free run in the locomotor activity rhythm of the field mouse Mus booduga under skeleton photoperiodic regimes. Biological rhythm Research., 29(2): 197-205.
  5. V. K. Sharma, M. K. Chandrashekaran and M. Singaravel (1998). Relationship between period and phase angle differences in Mus booduga under abrupt versus gradual light-dark transitions Naturwissen., 85:183-186.
  6. M. Singaravel, V. K. Sharma and R. Subbaraj (1998). Periodically varying sensitivity to melatonin in a mammalian circadian system. Current Science., 75(1): 51-54.
  7. J. Balasingh, S. S. Isaac, M. Singaravel, N. G. Nair and R. Subbaraj (1998). Parturition and mother infant relations in the Indian false vampire bat Megaderma lyra. Behavioural Processess., 44: 45-49.
  8. V. K. Sharma, M. K. Chandrashekaran, M. Singaravel and R. Subbaraj (1998). Ultraviolet light evoked phase shifts in the locomotor activity rhythm of the field mouse Mus booduga. Journal of photochemistry and photobiology B: Biology., 45(2): 83-86.
  9. V. K. Sharma, M. K. Chandrashekaran, M. Singaravel and R. Subbaraj (1999). Relationship between light intensity and phase resetting in a mammalian circadian system. Journal of Experimental Zoology., 283: 181-185.
  10. V. K. Sharma, M. Singaravel, R. Subbaraj and M. K. Chandrashekaran (1999). Locomotor activity rhythm in the field mouse Mus booduga phase shifts to melatonin injections in a dose dependent manner. Biological rhythm Research., 30(3): 313-320.
  11. V. K. Sharma, M. K. Chandrashekaran, M. Singaravel and R. Subbaraj (1999). In the field mouse Mus booduga melatonin phase response curves (PRCs) have a different time course and waveform relative to light PRC. Journal of Pineal Research., 26(3): 153-158.
  12. V. K. Sharma, M. Singaravel, R. Subbaraj and M. K. Chandrashekaran (1999). Timely administration of melatonin accelerates re-entrainment to phase shifted light dark cycles in the field mouse Mus booduga. Chronobiology International., 16(2): 163-170.
  13. V. K. Sharma, M. Singaravel and R. Subbaraj (1999). Ultraviolet light induced phase response curve for the locomotor activity rhythm of the field mouse Mus booduga. Naturwissen., 86: 96-97.
  14. M. Singaravel and K. Tomioka (2002). Pigment-dispersing factor induces phase shifts of circadian locomotor rhythm in the cricket Gryllus bimaculatus. Journal of Photoscience., 9: 243-245.
  15. M. Singaravel, A. Conti, S. R. Pandi Perumal, C. Tettamanti, G. J. M. Maestroni and C. Haldar (2002). Melatonin administration: time and dose determine the rate of re-entrainment in the mammalian system. In: Treatise on pineal gland and melatonin (C. Haldar, M. Singaravel and S. K. Maitra – Editors), Science Publishers, Plymouth, UK, pp.323-338.
  16. A. Conti, C. Tettamanti, M. Singaravel, C. Haldar, S. R. Pandi Perumal and G. J. M. Maestroni (2002). Melatonin: An ubiquitous and evolutionary hormone. In: Treatise on pineal gland and melatonin (C. Haldar, M. Singaravel and S. K. Maitra – Editors), Science Publishers, Plymouth, UK, pp. 105-143.
  17. M. Singaravel, Fujisawa, Y., Hisada, M., Saifullah, A. S. M. and Tomioka, K. (2003). Phase shifts of the circadian locomotor rhythm induced by pigment-dispersing factor in the cricket Gryllus bimaculatus. Zoological Science 20: 1347-1354.
  18. C. Haldar, S.S. Singh, S. Rai, K. Skwarlo-Sonta, J. Pawlak and M. Singaravel (2008). Melatonin and Immunomodulation: Involvement of the Neuro-Endocrine Network. In: Experimental endocrinology and reproductive biology (C. Haldar, M. Singaravel, S. R. Pandi Perumal and D. P. Cardinali – Editors), IBH Science Publishers, New Delhi, pp 297-314.
  19. Chaturvedi CM, Singh VP, Singh P, Basu P, Singaravel M, Shukla RK, Dhawan A, Pati AK, Gangwar RK and Singh SP (2011). 2.45 Ghz (CW) microwave irradiation alters circadian organization, spatial memory, DNA structure in the brain cells and blood cell counts of male mice, Mus musculus. Progress in Electromagentics Research B 29: 23-42
  20. B. Bharti, P. Basu, R. Mishra and M. Singaravel (2012). Effect of induced Dalton,s lymphoma on circadian locomotor activity of adult male mice. Biological rhythm Research 43:2, 215-223. (DOI: 10.1080/09291016.2011.560054).
  21. P. Basu, R. Tripathi, R. Mishra and M. Singaravel (2012). Effect of Chronic jet lag after induction of Dalton’s Lymphoma in male and female mice. Biological rhythm Research 43:3, 331-339 (DOI:10.1080/09291016.2011.579756).
  22. P. Basu, M. Singaravel and C. Haldar (2012). L-5-hydroxytryptophan resets the circadian locomotor activity rhythm of the nocturnal Indian pygmy field mouse, Mus terricolor. Naturwissenschaften 99:233-239; DOI 10.1007/s00114-012-0893-5.
  23. P. Basu and M. Singaravel (2012). Accurate and precise circadian locomotor activity rhythms in male and female Indian pygmy field mice, Mus terricolor. Biological Rhythm Research, DOI:10.1080/09291016.2012.721587.
  24. P. Basu and M. Singaravel (2012). Potentiation of light-induced phase shifts by 5-hydroxy-L-trptophan in pygmy field mice: a preliminary report. Biological Rhythm Research (Accepted; Ref. No. BRR52WJR12; ID: 730889; DOI:10.1080/09291016. 2012. 730889).
  25. P. Basu and M. Singaravel (2013). Acceleration of re-entrainment during a 6-h acute jet lag simulation by 5-hydroxy-l-tryptophan in pygmy field mice. Biological Rhythm Research (Accepted; DOI:10.1080/09291016.2013.770294).
  26. P. Basu and M. Singaravel (2013). 5-hydroxy-l-tryptophan entrains the free-running rhythm in constant darkness in pygmy mice. Biological Rhythm Research (Accepted; Ref. BRR86WJR12).

B. Books Edited:

  1. C. Haldar, M. Singaravel and S. K. Maitra (2002).Treatise on Pineal Gland. Science Publishers, Plymouth, UK.
  2. C. Haldar, M. Singaravel, S. R. Pandi-Perumal and D. P. Cardinali (2008).Experimental Endocrinology and Reporductive Biology. Science Publishers, Plymouth, UK.
  3. D. Kumar, N. Rastogi and M. Singaravel (2009). Functional Biodiversity and Ecophysiology of Animals. Pilgrim Press, Varanasi, India.
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